Paramedic Science (Medical) Essay Example | Topics and Well Written Essays - 2000 words

Paramedic Science (Medical) - Essay Example The area deprived of blood supply is said to have suffered ischemic injury. The ischemic injury, if severe enough to cause the complete block of oxygen and nutrients causes death of the heart tissue, which is termed as Myocardial Infarction (Guyton et al 200, Ganong 2005). The blood vessels supplying the heart are called coronary arteries. There are three main coronary arteries which supply different areas of heart along with their branches. These are 1) Right coronary artery, 2) Left anterior descending artery, 3) Left circumflex artery. Above 90% cases of myocardial infarction occur as a result of coronary artery blockage, thus the disease is also referred to as coronary artery disease (CAD). The most common and dangerous cause of coronary artery obstruction, and thus MI is Atherosclerosis. Atherosclerosis refers to the narrowing of arteries because of accumulation of atherosclerotic plaques. These plaques are basically thrombi composed of lipid foam cells (cholesterol) and differe nt cell components including smooth muscle, macrophages and collagen fibres. In most instances, the ischemic myocardial infarction is precipitated by the phenomenon called acute plaque change. Acute plaque change results from the rupture of pre-existing thrombi that partially occlude the lumen. The rupture exposes the underlying thrombogenic endothelium. The plaques are also termed as vulnerable plaques as they contain lipids in high amounts, along with collagen fibres and inflammatory cells. When ruptured, the reactivity of these components causes the inflammatory destabilization and result in the infarction (Libby P 2001). The acute phase reactant, C reactive protein (CRP) is thus found to be high during the acute myocardial infarction (Blake et al 2003). The infarction can occur in either of the two patterns, complete occlusion of a single coronary artery referred to as transmural infarct, which results in complete ischemia of the area supplied by that particular coronary artery. Subendocardial infarcts on the other hand occlude the arteries incompletely, and thus allow some perfusion. But since subendocardium is the least perused area of the myocardium, it is more prone to ischemic death. The aim of reperfusion is to save the viable muscle from necrosis (Huber et al 1996). The myocardial injury is reversible for up to 30 minutes after the ischemic attack, thereafter the injury becomes irreversible. The entire muscle becomes necrotic within six hours, if the collateral arteries are not well developed (Robbins et al 2005, Mohan 2007). The development of atherosclerotic plaques and pathogenesis of the process into the myocardial infarction is a complex one. It is a chronic disease taking years to evolve before it causes any modifiable consequences. The evolvement is subtle and the resultant damage is severe. The pathogenesis of the disease involves several factors. The balance among these factors in the long run determines the outcome of the condition. These factors can either be modifiable or non-modifiable. The modifiable factors are the ones that a person can control by bringing about certain changes. They include controlling the level of fats in diet, cessation of smoking, regular exercise and maintaining the blood pressure in the normal range (Manson et al 1996). The hyperlipidemias, i.e. elevated low density lipoproteins and

Military Regimes in African Countries Essay Example | Topics and Well Written Essays - 2000 words

Military Regimes in African Countries - Essay Example The discussions will entail logical arguments behind the various military regimes that have occurred in Africa. The paper will give an analysis of the various military regimes that have taken place in Africa since independence to modern days. Introduction The focus on military regimes can be traced to the period after 1950 when most African countries gained independence. There was a considerable increase in the number of military coups during the 1960s, 70s, and 80s. During this period, a large number of military regimes emerged all over the world. In 1979, fourteen military regimes rose to power in sub-Saharan Africa. Besides the military regimes in Sub-saharan Africa, other regimes held power in Latin America, North Africa, Arab states, South East Asia and East Asia (Falola 2002, p. 235) Because of the tremendous rise of African military regimes, political scientists, historians, sociologists, and economists had a keen interest in studying this form of government. Africa witnessed seventy-one military coups between 1950 and 1990. Since African nations gained independence, a number of military regimes have overthrown the ruling civilian regimes. The military coups replace the government and introduce military rule. In most instances, the military leaders, who take over governance, introduce dictatorial rules (Kieh & Agbese 2004, p. 20). Some of the famous military coups that have taken place in Africa include the Ghanaian coup in 1966, Libyan military coup in 1969 led by Muammar Gaddafi and the Ugandan coup in 1971 led by Idi Amin. Gaddafi led a group of young Libyan military officers in a bloodless coup that saw the overthrowing of King Idris I. In Uganda, Idi Amin succeeded in ending the rule of Milton Obote. Other military coups have happened in countries such as Nigeria, Congo, Togo, among others (Baynham 1986, p. 38). Rating performance of military regimes in Africa Military coups in Africa can be explained by general factors applicable to the entire cont inent. A keen look at the past military coups indicates a common trend in military coups. Almost all countries in Africa that have had military coups seem to have the same reasons for the eruption of the military coups. From 1960 to 1970, a number of African nations witnessed military coups. Historians have regarded this period as a decade of coups in Africa (Kieh & Agbese 2004, p. 22). Once a coup erupted in one country, it became a phenomenon in other nations. Coups swept across the entire African continent at an alarming rate. Based on this, the rise of military regimes in Africa emerges from general factors applicable to the entire continent. The paper will now focus on the factors that have led to the rise of military regimes in Africa. In an attempt to preserve authority, states have embraced the use of coercion. As a result, some government institutions play the role of enhancing coercion. This reality has significantly directed debates surrounding politics in postcolonial Af rica. The government needs coercive agencies, such as the police and military, which should be obedient to political leaders. However, this has not succeeded in Africa. In many instances, the military has used violent means to initiate coup d’etats. This is a contradiction since the military should manage violence on behalf of the state (Thomson 2010, p. 135). A notable factor responsible for military coups in A